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Splenic glucocorticoid resistance following psychosocial stress requires physical injury

Mice exposed to chronic subordinate colony housing (CSC) stress show glucocorticoid (GC) resistance of in vitro lipopolysaccharide (LPS)-stimulated splenocytes, increased anxiety and colitis. Similar effects were reported in wounded mice exposed to social disruption (SDR). Here we show that CSC expo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Foertsch, Sandra, Füchsl, Andrea M., Faller, Sandra D., Hölzer, Hannah, Langgartner, Dominik, Messmann, Joanna, Strauß, Gudrun, Reber, Stefan O.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691078/
https://ncbi.nlm.nih.gov/pubmed/29146967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15897-2
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