Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25

The Plasmodium falciparum Pfs25 protein (Pfs25) is a leading malaria transmission-blocking vaccine antigen. Pfs25 vaccination is intended to elicit antibodies that inhibit parasite development when ingested by Anopheles mosquitoes during blood meals. The Pfs25 three-dimensional structure has remaine...

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Publicado en:Nat Commun
Main Authors: Scally, Stephen W., McLeod, Brandon, Bosch, Alexandre, Miura, Kazutoyo, Liang, Qi, Carroll, Sean, Reponen, Sini, Nguyen, Ngan, Giladi, Eldar, Rämisch, Sebastian, Yusibov, Vidadi, Bradley, Allan, Lemiale, Franck, Schief, William R., Emerling, Daniel, Kellam, Paul, King, C. Richter, Julien, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5691035/
https://ncbi.nlm.nih.gov/pubmed/29146922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01924-3
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