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Extracellular ISG15 Signals Cytokine Secretion Through the LFA-1 Integrin Receptor
ISG15 is a ubiquitin-like protein that functions in innate immunity both as an intracellular protein modifier and as an extracellular signaling molecule that stimulates IFN-γ secretion. The extracellular function, important for resistance to mycobacterial disease, has remained biochemically uncharac...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5690536/ https://ncbi.nlm.nih.gov/pubmed/29100055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.10.003 |
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