Stromal interaction molecule 1 haploinsufficiency causes maladaptive response to pressure overload

Stromal interaction molecule 1 (STIM1), an endo/sarcoplasmic reticulum Ca(2+) sensor, has been shown to control a Ca(2+)-dependent signal that promotes cardiac hypertrophy. However, whether STIM1 has adaptive role that helps to protect against cardiac overload stress remains unknown. We hypothesized...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ohba, Takayoshi, Watanabe, Hiroyuki, Murakami, Manabu, Iino, Kenji, Adachi, Takeshi, Baba, Yoshihiro, Kurosaki, Tomohiro, Ono, Kyoichi, Ito, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690472/
https://ncbi.nlm.nih.gov/pubmed/29145451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187950
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