Analytical Pitfalls of Therapeutic Drug Monitoring of Thiopurines in Patients With Inflammatory Bowel Disease

The use of thiopurines in the treatment of inflammatory bowel disease (IBD) can be optimized by the application of therapeutic drug monitoring. In this procedure, 6-thioguanine nucleotides (6-TGN) and 6-methylmercaptopurine (6-MMP) metabolites are monitored and related to therapeutic response and ad...

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Bibliografske podrobnosti
izdano v:Ther Drug Monit
Main Authors: Simsek, Melek, Meijer, Berrie, Mulder, Chris J. J., van Bodegraven, Adriaan A., de Boer, Nanne K. H.
Format: Artigo
Jezik:Inglês
Izdano: Therapeutic Drug Monitoring 2017
Teme:
Review Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690305/
https://ncbi.nlm.nih.gov/pubmed/29040228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000455
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