Analytical Pitfalls of Therapeutic Drug Monitoring of Thiopurines in Patients With Inflammatory Bowel Disease

The use of thiopurines in the treatment of inflammatory bowel disease (IBD) can be optimized by the application of therapeutic drug monitoring. In this procedure, 6-thioguanine nucleotides (6-TGN) and 6-methylmercaptopurine (6-MMP) metabolites are monitored and related to therapeutic response and ad...

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Bibliographic Details
Published in:Ther Drug Monit
Main Authors: Simsek, Melek, Meijer, Berrie, Mulder, Chris J. J., van Bodegraven, Adriaan A., de Boer, Nanne K. H.
Format: Artigo
Language:Inglês
Published: Therapeutic Drug Monitoring 2017
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690305/
https://ncbi.nlm.nih.gov/pubmed/29040228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000455
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