Single-molecule force spectroscopy of protein-membrane interactions

Many biological processes rely on protein–membrane interactions in the presence of mechanical forces, yet high resolution methods to quantify such interactions are lacking. Here, we describe a single-molecule force spectroscopy approach to quantify membrane binding of C2 domains in Synaptotagmin-1 (...

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Publicado en:eLife
Autores principales: Ma, Lu, Cai, Yiying, Li, Yanghui, Jiao, Junyi, Wu, Zhenyong, O'Shaughnessy, Ben, De Camilli, Pietro, Karatekin, Erdem, Zhang, Yongli
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690283/
https://ncbi.nlm.nih.gov/pubmed/29083305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30493
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