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Exposure of Induced Pluripotent Stem Cell‐Derived Vascular Endothelial and Smooth Muscle Cells in Coculture to Hemodynamics Induces Primary Vascular Cell‐Like Phenotypes

Human induced pluripotent stem cells (iPSCs) can be differentiated into vascular endothelial (iEC) and smooth muscle (iSMC) cells. However, because iECs and iSMCs are not derived from an intact blood vessel, they represent an immature phenotype. Hemodynamics and heterotypic cell:cell communication p...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Transl Med
Autori principali: Collado, Maria S., Cole, Banumathi K., Figler, Robert A., Lawson, Mark, Manka, David, Simmers, Michael B., Hoang, Steve, Serrano, Felipe, Blackman, Brett R., Sinha, Sanjay, Wamhoff, Brian R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689791/
https://ncbi.nlm.nih.gov/pubmed/28628273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.17-0004
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