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Tracheal Replacement Therapy with a Stem Cell‐Seeded Graft: Lessons from Compassionate Use Application of a GMP‐Compliant Tissue‐Engineered Medicine

Tracheal replacement for the treatment of end‐stage airway disease remains an elusive goal. The use of tissue‐engineered tracheae in compassionate use cases suggests that such an approach is a viable option. Here, a stem cell‐seeded, decellularized tissue‐engineered tracheal graft was used on a comp...

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Détails bibliographiques
Publié dans:Stem Cells Transl Med
Auteurs principaux: Elliott, Martin J., Butler, Colin R., Varanou‐Jenkins, Aikaterini, Partington, Leanne, Carvalho, Carla, Samuel, Edward, Crowley, Claire, Lange, Peggy, Hamilton, Nicholas J., Hynds, Robert E., Ansari, Tahera, Sibbons, Paul, Fierens, Anja, McLaren, Claire, Roebuck, Derek, Wallis, Colin, Muthialu, Nagarajan, Hewitt, Richard, Crabbe, David, Janes, Sam M., De Coppi, Paolo, Lowdell, Mark W., Birchall, Martin A.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689750/
https://ncbi.nlm.nih.gov/pubmed/28544662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.16-0443
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