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High uric acid (UA) downregulates bone alkaline phosphatase (BALP) expression through inhibition of its promoter activity

Bone metastases often occur in prostate cancers, lung cancers and breast cancers. Bone alkaline phosphatase (BALP) is one of the most commonly used serological markers for clinical evaluation of bone metabolism. Here, we reported that high concentrations of uric acid (UA) caused decrease of BALP lev...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wu, Zhi-Qi, Chen, Xiao-Ting, Xu, Yan-Yan, Tian, Ming-Jie, Chen, Hai-Yan, Zhou, Guo-Ping, Xu, Hua-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689639/
https://ncbi.nlm.nih.gov/pubmed/29156749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21110
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