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Targeting protein quality control pathways in breast cancer

The efficient production, folding, and secretion of proteins is critical for cancer cell survival. However, cancer cells thrive under stress conditions that damage proteins, so many cancer cells overexpress molecular chaperones that facilitate protein folding and target misfolded proteins for degrad...

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Bibliografiske detaljer
Udgivet i:BMC Biol
Main Authors: Sannino, Sara, Brodsky, Jeffrey L.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689203/
https://ncbi.nlm.nih.gov/pubmed/29145850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-017-0449-4
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