Biochemical and structural bioinformatics studies of fungal CutA nucleotidyltransferases explain their unusual specificity toward CTP and increased tendency for cytidine incorporation at the 3′-terminal positions of synthesized tails

Noncanonical RNA nucleotidyltransferases (NTases), including poly(A), poly(U) polymerases (PAPs/PUPs), and C/U-adding enzymes, modify 3′-ends of different transcripts affecting their functionality and stability. They contain PAP/OAS1 substrate-binding domain (SBD) with inserted NTase domain. Aspergi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:RNA
Autores principales: Kobyłecki, Kamil, Kuchta, Krzysztof, Dziembowski, Andrzej, Ginalski, Krzysztof, Tomecki, Rafał
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689010/
https://ncbi.nlm.nih.gov/pubmed/28947555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.061010.117
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares