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Effects of regulatory BC1 RNA deletion on synaptic plasticity, learning, and memory

Nonprotein coding dendritic BC1 RNA regulates translation of mRNAs in neurons. We examined two lines of BC1 knockout mice and report that loss of BC1 RNA exaggerates group I mGluR-stimulated LTD of the Schaffer collateral synapse, with one of the lines showing a much more enhanced DHPG-induced LTD t...

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Publicat a:Learn Mem
Autors principals: Chung, Ain, Dahan, Nessy, Alarcon, Juan Marcos, Fenton, André A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688958/
https://ncbi.nlm.nih.gov/pubmed/29142061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.045617.117
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