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DNPEP is not the only peptidase that produces SPAK fragments in kidney
SPAK (STE20/SPS1‐related proline/alanine‐rich kinase) regulates Na(+) and Cl(−) reabsorption in the distal convoluted tubule, and possibly in the thick ascending limb of Henle. This kinase phosphorylates and activates the apical Na‐Cl cotransporter in the DCT. Western blot analysis reveals that SPAK...
Guardat en:
| Publicat a: | Physiol Rep |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5688775/ https://ncbi.nlm.nih.gov/pubmed/29122955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13479 |
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