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Methylxanthines induce structural and functional alterations of the cardiac system in zebrafish embryos

BACKGROUND: Zebrafish embryos are emerging as a model for pharmacological and toxicological studies. We used zebrafish embryos to study the general toxicity and cardiovascular effects of eight methylxanthines: aminophylline, caffeine, diprophylline, doxofylline, etophylline, 3-isobutyl-1-methylxanth...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Basnet, Ram Manohar, Zizioli, Daniela, Guarienti, Michela, Finazzi, Dario, Memo, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688754/
https://ncbi.nlm.nih.gov/pubmed/29141695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-017-0179-9
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