Active fraction (HS7) from Taiwanofungus camphoratus inhibits AKT-mTOR, ERK and STAT3 pathways and induces CDK inhibitors in CL1-0 human lung cancer cells

BACKGROUND: The non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide. In NSCLC, the oncogenic AKT-mTOR, ERK and STAT3 pathways are commonly dysregulated and have emerged as attractive targets for therapeutic developments. In a relatively limited subset of NSCLC, these pa...

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Udgivet i:Chin Med
Main Authors: Lai, I-Chun, Lai, Gi-Ming, Chow, Jyh-Ming, Lee, Hsin-Lun, Yeh, Chuan-Feng, Li, Chi-Han, Yan, Jiann-Long, Chuang, Shuang-En, Whang-Peng, Jacqueline, Bai, Kuan-Jen, Yao, Chih-Jung
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688709/
https://ncbi.nlm.nih.gov/pubmed/29177004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13020-017-0154-9
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