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Simulation of Reversible Protein–Protein Binding and Calculation of Binding Free Energies Using Perturbed Distance Restraints

[Image: see text] Virtually all biological processes depend on the interaction between proteins at some point. The correct prediction of biomolecular binding free-energies has many interesting applications in both basic and applied pharmaceutical research. While recent advances in the field of molec...

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Publicat a:J Chem Theory Comput
Autors principals: Perthold, Jan Walther, Oostenbrink, Chris
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2017
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688412/
https://ncbi.nlm.nih.gov/pubmed/28898077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.7b00706
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