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SensorFRET: A Standardless Approach to Measuring Pixel-based Spectral Bleed-through and FRET Efficiency using Spectral Imaging

Fluorescence microscopy of FRET-based biosensors allow nanoscale interactions to be probed in living cells. This paper describes a novel approach to spectrally resolved fluorescence microscopy, termed sensorFRET, that enables quantitative measurement of FRET efficiency. This approach is an improveme...

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Pubblicato in:Sci Rep
Autori principali: Arsenovic, Paul T., Mayer, Carl R., Conway, Daniel E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688180/
https://ncbi.nlm.nih.gov/pubmed/29142199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15411-8
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