Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis

Spondyloarthritis encompasses a group of common inflammatory diseases thought to be driven by IL-17A-secreting type-17 lymphocytes. Here we show increased numbers of GM-CSF-producing CD4 and CD8 lymphocytes in the blood and joints of patients with spondyloarthritis, and increased numbers of IL-17A(+...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Al-Mossawi, M. H., Chen, L., Fang, H., Ridley, A., de Wit, J., Yager, N., Hammitzsch, A., Pulyakhina, I., Fairfax, B. P., Simone, D., Yi, Yao, Bandyopadhyay, S., Doig, K., Gundle, R, Kendrick, B., Powrie, F., Knight, J. C., Bowness, P.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688161/
https://ncbi.nlm.nih.gov/pubmed/29142230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01771-2
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