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Maternal Exposure to Iodine Excess Throughout Pregnancy and Lactation Induces Hypothyroidism in Adult Male Rat Offspring

This study aimed to investigate the consequences of maternal exposure to iodine excess (IE; 0.6 mg NaI/L) throughout pregnancy and lactation on the hypothalamus-pituitary-thyroid axis of the male offspring in adulthood. Maternal IE exposure increased hypothalamic Trh mRNA expression and pituitary Ts...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Serrano-Nascimento, Caroline, Salgueiro, Rafael Barrera, Pantaleão, Thiago, Corrêa da Costa, Vânia Maria, Nunes, Maria Tereza
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688151/
https://ncbi.nlm.nih.gov/pubmed/29142304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15529-9
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