The Immunomodulatory Drug Glatiramer Acetate is Also an Effective Antimicrobial Agent that Kills Gram-negative Bacteria

Classic drug development strategies have failed to meet the urgent clinical needs in treating infections with Gram-negative bacteria. Repurposing drugs can lead to timely availability of new antibiotics, accelerated by existing safety profiles. Glatiramer acetate (GA) is a widely used and safe formu...

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Udgivet i:Sci Rep
Main Authors: Christiansen, Stig Hill, Murphy, Ronan A., Juul-Madsen, Kristian, Fredborg, Marlene, Hvam, Michael Lykke, Axelgaard, Esben, Skovdal, Sandra M., Meyer, Rikke Louise, Sørensen, Uffe B. Skov, Möller, Arne, Nyengaard, Jens Randel, Nørskov-Lauritsen, Niels, Wang, Mikala, Gadjeva, Mihaela, Howard, Kenneth A., Davies, Jane C., Petersen, Eskild, Vorup-Jensen, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688084/
https://ncbi.nlm.nih.gov/pubmed/29142299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15969-3
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