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Photoredox Enables the Construction of 1,1-Difluoroalkene Carbonyl Mimics

We describe a facile, scalable route to access functional group-rich gem-difluoroalkenes. Using visible-light activated catalysts in conjunction with an arsenal of carbon-radical precursors, an array of trifluoromethyl-substituted alkenes undergoes radical defluorinative alkylation. Non-stabilized p...

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Publicado en:Angew Chem Int Ed Engl
Main Authors: Lang, Simon B., Wiles, Rebecca J., Kelly, Christopher B., Molander, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5688010/
https://ncbi.nlm.nih.gov/pubmed/28960656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201709487
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