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Selection for avian leukosis virus integration sites determines the clonal progression of B-cell lymphomas

Avian leukosis virus (ALV) is a simple retrovirus that causes a wide range of tumors in chickens, the most common of which are B-cell lymphomas. The viral genome integrates into the host genome and uses its strong promoter and enhancer sequences to alter the expression of nearby genes, frequently in...

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Publicat a:PLoS Pathog
Autors principals: Malhotra, Sanandan, Winans, Shelby, Lam, Gary, Justice, James, Morgan, Robin, Beemon, Karen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687753/
https://ncbi.nlm.nih.gov/pubmed/29099869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006708
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