Saikosaponin A inhibits IL-1β-induced inflammatory mediators in human osteoarthritis chondrocytes by activating LXRα

Saikosaponin a (SSa), one of the main active components of Bupleurum falcatum, has been reported to have anti-inflammatory effect. In the present study, we investigated the anti-inflammatory effect of SSa on IL-1β-stimulated human osteoarthritis chondrocytes. The cells were pretreated with SSa 12 h...

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Sparad:
Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Gao, Hang, Song, Yanyan, Li, Dongsong, Feng, Wei, Liu, Jianguo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687659/
https://ncbi.nlm.nih.gov/pubmed/29179489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21495
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