Notochordal-cell derived extracellular vesicles exert regenerative effects on canine and human nucleus pulposus cells

During intervertebral disc ageing, chondrocyte-like cells (CLCs) replace notochordal cells (NCs). NCs have been shown to induce regenerative effects in CLCs. Since vesicles released by NCs may be responsible for these effects, we characterized NC-derived extracellular vesicles (EVs) and determined t...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Bach, Frances, Libregts, Sten, Creemers, Laura, Meij, Björn, Ito, Keita, Wauben, Marca, Tryfonidou, Marianna
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687651/
https://ncbi.nlm.nih.gov/pubmed/29179481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21483
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