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Anti-PD-1 Antibody Treatment Promotes Clearance of Persistent Cryptococcal Lung Infection in Mice
Activation of immunomodulatory pathways in response to invasive fungi can impair clearance and promote persistent infections. The Programmed Cell Death Protein-1 (PD-1) signaling pathway inhibits immune effector responses against tumors and immune checkpoint inhibitors that block this pathway are be...
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| Publicado en: | J Immunol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5687305/ https://ncbi.nlm.nih.gov/pubmed/29038249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700840 |
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