Homologated amino acids with three vicinal fluorines positioned along the backbone: development of a stereoselective synthesis

Backbone-extended amino acids have a variety of potential applications in peptide and protein science, particularly if the geometry of the amino acid is controllable. Here we describe the synthesis of δ-amino acids that contain three vicinal C–F bonds positioned along the backbone. The ultimately su...

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Bibliografische gegevens
Gepubliceerd in:Beilstein J Org Chem
Hoofdauteurs: Cheerlavancha, Raju, Ahmed, Ahmed, Leung, Yun Cheuk, Lawer, Aggie, Liu, Qing-Quan, Cagnes, Marina, Jang, Hee-Chan, Hu, Xiang-Guo, Hunter, Luke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Beilstein-Institut 2017
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Full Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687047/
https://ncbi.nlm.nih.gov/pubmed/29181111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.228
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