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Differential context-specific impact of individual core promoter elements on transcriptional dynamics

Eukaryotic transcription occurs in bursts that vary in size and frequency, but the contribution of individual core promoter elements to transcriptional bursting is not known. Here we analyze the relative contributions to bursting of the individual core promoter elements—CCAAT, TATAA-like, Sp1BS, and...

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Publicado en:Mol Biol Cell
Main Authors: Hendy, Oliver, Campbell, John, Weissman, Jocelyn D., Larson, Daniel R., Singer, Dinah S.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687036/
https://ncbi.nlm.nih.gov/pubmed/28931597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-06-0408
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