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Differential context-specific impact of individual core promoter elements on transcriptional dynamics

Eukaryotic transcription occurs in bursts that vary in size and frequency, but the contribution of individual core promoter elements to transcriptional bursting is not known. Here we analyze the relative contributions to bursting of the individual core promoter elements—CCAAT, TATAA-like, Sp1BS, and...

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Bibliografske podrobnosti
izdano v:Mol Biol Cell
Main Authors: Hendy, Oliver, Campbell, John, Weissman, Jocelyn D., Larson, Daniel R., Singer, Dinah S.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687036/
https://ncbi.nlm.nih.gov/pubmed/28931597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-06-0408
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