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Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs

BACKGROUND: MicroRNAs (miRNAs) have been shown to play an important role in pathological initiation, progression and maintenance. Because identification in the laboratory of disease-related miRNAs is not straightforward, numerous network-based methods have been developed to predict novel miRNAs in s...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Le, Duc-Hau, Verbeke, Lieven, Son, Le Hoang, Chu, Dinh-Toi, Pham, Van-Huy
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686822/
https://ncbi.nlm.nih.gov/pubmed/29137601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1924-1
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