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ClusterTAD: an unsupervised machine learning approach to detecting topologically associated domains of chromosomes from Hi-C data

BACKGROUND: With the development of chromosomal conformation capturing techniques, particularly, the Hi-C technique, the study of the spatial conformation of a genome is becoming an important topic in bioinformatics and computational biology. The Hi-C technique can generate genome-wide chromosomal i...

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Publicat a:BMC Bioinformatics
Autors principals: Oluwadare, Oluwatosin, Cheng, Jianlin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686814/
https://ncbi.nlm.nih.gov/pubmed/29137603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1931-2
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