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Discrete Dynamical Modeling of Influenza Virus Infection Suggests Age-Dependent Differences in Immunity

Immunosenescence, an age-related decline in immune function, is a major contributor to morbidity and mortality in the elderly. Older hosts exhibit a delayed onset of immunity and prolonged inflammation after an infection, leading to excess damage and a greater likelihood of death. Our study applies...

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發表在:J Virol
Main Authors: Keef, Ericka, Zhang, Li Ang, Swigon, David, Urbano, Alisa, Ermentrout, G. Bard, Matuszewski, Michael, Toapanta, Franklin R., Ross, Ted M., Parker, Robert S., Clermont, Gilles
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686742/
https://ncbi.nlm.nih.gov/pubmed/28904202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00395-17
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