Mutations in the Fusion Protein of Measles Virus That Confer Resistance to the Membrane Fusion Inhibitors Carbobenzoxy-d-Phe-l-Phe-Gly and 4-Nitro-2-Phenylacetyl Amino-Benzamide

The inhibitors carbobenzoxy (Z)-d-Phe-l-Phe-Gly (fusion inhibitor peptide [FIP]) and 4-nitro-2-phenylacetyl amino-benzamide (AS-48) have similar efficacies in blocking membrane fusion and syncytium formation mediated by measles virus (MeV). Other homologues, such as Z-d-Phe, are less effective but m...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Ha, Michael N., Delpeut, Sébastien, Noyce, Ryan S., Sisson, Gary, Black, Karen M., Lin, Liang-Tzung, Bilimoria, Darius, Plemper, Richard K., Privé, Gilbert G., Richardson, Christopher D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Virus-Cell Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686717/
https://ncbi.nlm.nih.gov/pubmed/28904193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01026-17
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