Hypothalamic-Pituitary-Ovarian Axis Reactivation by Kisspeptin-10 in Hyperprolactinemic Women With Chronic Amenorrhea

CONTEXT: Hyperprolactinemia-induced hypogonadotropic amenorrhea (hPRL-HA) is a major cause of hypothalamic gonadotrophin-releasing hormone (GnRH) deficiency in women. In hyperprolactinemic mice, we previously demonstrated that hypothalamic kisspeptin (Kp) expression was diminished and that Kp admini...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Millar, Robert P., Sonigo, Charlotte, Anderson, Richard A., George, Jyothis, Maione, Luigi, Brailly-Tabard, Sylvie, Chanson, Philippe, Binart, Nadine, Young, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Clinical Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686678/
https://ncbi.nlm.nih.gov/pubmed/29264460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2017-00328
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