PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice

DNA replication is frequently perturbed by intrinsic, as well as extrinsic, genotoxic stress. At damaged forks, DNA replication and repair activities require proper coordination to maintain genome integrity. We show here that PARI antirecombinase plays an essential role in modulating the initial res...

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Publicado en:Mol Cell Biol
Autores principales: Mochizuki, Ayako L., Katanaya, Ami, Hayashi, Eri, Hosokawa, Mihoko, Moribe, Emiko, Motegi, Akira, Ishiai, Masamichi, Takata, Minoru, Kondoh, Gen, Watanabe, Hitomi, Nakatsuji, Norio, Chuma, Shinichiro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686578/
https://ncbi.nlm.nih.gov/pubmed/28894029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00117-17
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