Somatotroph-Specific Aip-Deficient Mice Display Pretumorigenic Alterations in Cell-Cycle Signaling

Patients with familial isolated pituitary adenoma are predisposed to pituitary adenomas, which in a subset of cases is due to germline inactivating mutations of the aryl hydrocarbon receptor–interacting protein (AIP) gene. Using Cre/lox and Flp/Frt technology, a conditional mouse model was generated...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Gillam, Mary P., Ku, Cheol Ryong, Lee, Yang Jong, Kim, Jean, Kim, Se Hoon, Lee, Sue Ji, Hwang, Byungjin, Koo, JaeHyung, Kineman, Rhonda D., Kiyokawa, Hiroaki, Lee, Eun Jig
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686555/
https://ncbi.nlm.nih.gov/pubmed/29264469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2016-1004
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