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A Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Comparison Design Trial of Adjunctive Riluzole for Treatment-Resistant Major Depressive Disorder

Riluzole is a glutamate-modulating agent with neuroprotective properties approved for use in amyotrophic lateral sclerosis. The efficacy and safety of riluzole vs placebo as an adjunct to antidepressant medication in outpatients with major depressive disorder (MDD) was examined in a 3-site, 8-week,...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Mathew, Sanjay J, Gueorguieva, Ralitza, Brandt, Cynthia, Fava, Maurizio, Sanacora, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686483/
https://ncbi.nlm.nih.gov/pubmed/28553836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.106
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