miR-148a inhibits colitis and colitis-associated tumorigenesis in mice

miR-148a has been shown to regulate inflammation, immunity and the growth of certain tumors, but its roles in colitis and colorectal tumorigenesis remain largely undetermined. Here we found miR-148a-deficient mice to be more susceptible to colitis and colitis-associated tumorigenesis. Both were asso...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Differ
Hauptverfasser: Zhu, Yahui, Gu, Li, Li, Yajun, Lin, Xi, Shen, Hongxing, Cui, Kaisa, Chen, Li, Zhou, Feng, Zhao, Qiu, Zhang, Jinxiang, Zhong, Bo, Prochownik, Edward, Li, Youjun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686357/
https://ncbi.nlm.nih.gov/pubmed/28960206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.151
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