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Stimulation of primordial follicle assembly by estradiol-17β requires the action of bone morphogenetic protein-2 (BMP2)

Primordial follicle (PF) pool determines the availability of follicles for ovulation in all mammals. Premature depletion of the PF reserve leads to subfertility or infertility. Bone morphogenetic protein 2 (BMP2) promotes PF formation by facilitating oocyte and granulosa cell development. Estradiol-...

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Publicado en:Sci Rep
Main Authors: Chakraborty, Prabuddha, Roy, Shyamal K.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686124/
https://ncbi.nlm.nih.gov/pubmed/29138526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15833-4
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