Inhibition of Epithelial TNF-α Receptors by Purified Fruit Bromelain Ameliorates Intestinal Inflammation and Barrier Dysfunction in Colitis

Activation of the TNF-α receptor (TNFR) leads to an inflammatory response, and anti-TNF therapy has been administered to reduce inflammation symptoms and heal mucosal ulcers in inflammatory bowel disease (IBD). Bromelain, a complex natural mixture of proteolytic enzymes, has been shown to exert anti...

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Vydáno v:Front Immunol
Hlavní autoři: Zhou, Zijuan, Wang, Liang, Feng, Panpan, Yin, Lianhong, Wang, Chen, Zhi, Shengxu, Dong, Jianyi, Wang, Jingyu, Lin, Yuan, Chen, Dapeng, Xiong, Yongjian, Peng, Jinyong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686092/
https://ncbi.nlm.nih.gov/pubmed/29176974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01468
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