The Oncogenic Role of Tribbles 1 in Hepatocellular Carcinoma Is Mediated by a Feedback Loop Involving microRNA-23a and p53

Hepatocellular carcinoma (HCC) is a common malignancy associated with a high risk of recurrence and metastasis and a poor prognosis. Here, we examined the involvement of the pseudokinase Tribbles 1 (TRIB1), a scaffold protein associated with several malignancies, in HCC and investigated the underlyi...

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Bibliografiske detaljer
Udgivet i:Front Physiol
Main Authors: Ye, Ying, Wang, Guangdong, Wang, Guoyu, Zhuang, Juhua, He, Saifei, Song, Yanan, Ni, Jing, Xia, Wei, Wang, Jiening
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686088/
https://ncbi.nlm.nih.gov/pubmed/29176948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00789
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