Quorum Sensing Down-Regulation Counteracts the Negative Impact of Pseudomonas aeruginosa on CFTR Channel Expression, Function and Rescue in Human Airway Epithelial Cells

The function of cystic fibrosis transmembrane conductance regulator (CFTR) channels is crucial in human airways. However unfortunately, chronic Pseudomonas aeruginosa infection has been shown to impair CFTR proteins in non-CF airway epithelial cells (AEC) and to alter the efficiency of new treatment...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Maillé, Émilie, Ruffin, Manon, Adam, Damien, Messaoud, Hatem, Lafayette, Shantelle L., McKay, Geoffrey, Nguyen, Dao, Brochiero, Emmanuelle
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686086/
https://ncbi.nlm.nih.gov/pubmed/29177135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00470
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