Quorum Sensing Down-Regulation Counteracts the Negative Impact of Pseudomonas aeruginosa on CFTR Channel Expression, Function and Rescue in Human Airway Epithelial Cells

The function of cystic fibrosis transmembrane conductance regulator (CFTR) channels is crucial in human airways. However unfortunately, chronic Pseudomonas aeruginosa infection has been shown to impair CFTR proteins in non-CF airway epithelial cells (AEC) and to alter the efficiency of new treatment...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Maillé, Émilie, Ruffin, Manon, Adam, Damien, Messaoud, Hatem, Lafayette, Shantelle L., McKay, Geoffrey, Nguyen, Dao, Brochiero, Emmanuelle
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5686086/
https://ncbi.nlm.nih.gov/pubmed/29177135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00470
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