CRACM1 Multimers Form the Ion-Selective Pore of the CRAC Channel

Receptor-mediated Ca(2+) release from the endoplasmic reticulum (ER) is often followed by Ca(2+) entry through Ca(2+)-release-activated Ca(2+) (CRAC) channels in the plasma membrane [1–5]. RNAi screens have identified STIM1 as the putative ER Ca(2+) sensor [6–8] and CRACM1 (Orai1; [9–11]) as the put...

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Udgivet i:Curr Biol
Main Authors: Vig, Monika, Beck, Andreas, Billingsley, James M., Lis, Annette, Parvez, Suhel, Peinelt, Christine, Koomoa, Dana L., Soboloff, Jonathan, Gill, Donald L., Fleig, Andrea, Kinet, Jean-Pierre, Penner, Reinhold
Format: Artigo
Sprog:Inglês
Udgivet: 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685803/
https://ncbi.nlm.nih.gov/pubmed/16978865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2006.08.085
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