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Charge Influences Substrate Recognition and Self-Assembly of Hydrophobic FG Sequences

The nuclear pore complex controls the passage of molecules via hydrophobic phenylalanine-glycine (FG) domains on nucleoporins. Such FG domains consist of repeating units of FxFG, FG, or GLFG sequences, many of which are interspersed with highly charged amino acid sequences. Despite the high density...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Chen, Wesley G., Witten, Jacob, Grindy, Scott C., Holten-Andersen, Niels, Ribbeck, Katharina
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685782/
https://ncbi.nlm.nih.gov/pubmed/29117531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.08.058
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