Abundant expression of TIM-3, LAG-3, PD-1 and PD-L1 as immunotherapy checkpoint targets in effusions of mesothelioma patients

Malignant pleural mesothelioma (MPM) is an aggressive cancer with an increasing incidence, poor prognosis and limited effective treatment options. Hence, new treatment strategies are warranted which include immune checkpoint blockade approaches with encouraging preliminary data. Research on the immu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Marcq, Elly, Waele, Jorrit De, Audenaerde, Jonas Van, Lion, Eva, Santermans, Eva, Hens, Niel, Pauwels, Patrick, van Meerbeeck, Jan P., Smits, Evelien L.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685704/
https://ncbi.nlm.nih.gov/pubmed/29163783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21113
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