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Building Predictive Models of Genetic Circuits Using the Principle of Maximum Caliber

Learning the underlying details of a gene network is a major challenge in cellular and synthetic biology. We address this challenge by building a chemical kinetic model that utilizes information encoded in the stochastic protein expression trajectories typically measured in experiments. The applicab...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Firman, Taylor, Balázsi, Gábor, Ghosh, Kingshuk
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685677/
https://ncbi.nlm.nih.gov/pubmed/29117534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.08.057
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