Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene

Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma is characterized by 2p23/ALK aberrations, including the classic t(2;5)(p23;q35)/NPM1-ALK rearrangement present in ~80% of cases and several variant t(2p23/ALK) occurring in the remaining cases. The ALK fusion partners play a ke...

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Veröffentlicht in:Haematologica
Hauptverfasser: van der Krogt, Jo-Anne, Bempt, Marlies Vanden, Ferreiro, Julio Finalet, Mentens, Nicole, Jacobs, Kris, Pluys, Ursula, Doms, Kathleen, Geerdens, Ellen, Uyttebroeck, Anne, Pierre, Pascal, Michaux, Lucienne, Devos, Timothy, Vandenberghe, Peter, Tousseyn, Thomas, Cools, Jan, Wlodarska, Iwona
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685221/
https://ncbi.nlm.nih.gov/pubmed/28659337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.146571
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