Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease

Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation of lipid hydroperoxides to lethal levels. Emerging evidence suggests that ferroptosis represents an ancient vulnerability caused by the incorporation of polyunsaturated fatty acids into cellular membranes,...

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Publié dans:Cell
Auteurs principaux: Stockwell, Brent R., Angeli, Jose Pedro Friedmann, Bayir, Hülya, Bush, Ashley I., Conrad, Marcus, Dixon, Scott, Fulda, Simone, Gascon, Sergio, Hatzios, Stavroula K., Kagan, Valerian, Noel, Kay, Jiang, Xuejun, Linkermann, Andreas, Murphy, Maureen E., Overholtzer, Michael, Oyagi, Atsushi, Pagnussat, Gabriela, Park, Jason, Ran, Qitao, Rosenfeld, Craig S., Salnikow, Konstantin, Tang, Daolin, Torti, Frank, Torti, Suzy, Toyokuni, Shinya, Woerpel, K. A., Zhang, Donna D.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685180/
https://ncbi.nlm.nih.gov/pubmed/28985560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.021
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