Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease

Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation of lipid hydroperoxides to lethal levels. Emerging evidence suggests that ferroptosis represents an ancient vulnerability caused by the incorporation of polyunsaturated fatty acids into cellular membranes,...

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Publicado en:Cell
Autores principales: Stockwell, Brent R., Angeli, Jose Pedro Friedmann, Bayir, Hülya, Bush, Ashley I., Conrad, Marcus, Dixon, Scott, Fulda, Simone, Gascon, Sergio, Hatzios, Stavroula K., Kagan, Valerian, Noel, Kay, Jiang, Xuejun, Linkermann, Andreas, Murphy, Maureen E., Overholtzer, Michael, Oyagi, Atsushi, Pagnussat, Gabriela, Park, Jason, Ran, Qitao, Rosenfeld, Craig S., Salnikow, Konstantin, Tang, Daolin, Torti, Frank, Torti, Suzy, Toyokuni, Shinya, Woerpel, K. A., Zhang, Donna D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685180/
https://ncbi.nlm.nih.gov/pubmed/28985560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.021
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