Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease

Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation of lipid hydroperoxides to lethal levels. Emerging evidence suggests that ferroptosis represents an ancient vulnerability caused by the incorporation of polyunsaturated fatty acids into cellular membranes,...

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Publicat a:Cell
Autors principals: Stockwell, Brent R., Angeli, Jose Pedro Friedmann, Bayir, Hülya, Bush, Ashley I., Conrad, Marcus, Dixon, Scott, Fulda, Simone, Gascon, Sergio, Hatzios, Stavroula K., Kagan, Valerian, Noel, Kay, Jiang, Xuejun, Linkermann, Andreas, Murphy, Maureen E., Overholtzer, Michael, Oyagi, Atsushi, Pagnussat, Gabriela, Park, Jason, Ran, Qitao, Rosenfeld, Craig S., Salnikow, Konstantin, Tang, Daolin, Torti, Frank, Torti, Suzy, Toyokuni, Shinya, Woerpel, K. A., Zhang, Donna D.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685180/
https://ncbi.nlm.nih.gov/pubmed/28985560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.021
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