Hypoactivation and Dysconnectivity of a Frontostriatal Circuit During Goal-Directed Planning as an Endophenotype for Obsessive-Compulsive Disorder

BACKGROUND: The symptoms of obsessive-compulsive disorder (OCD) have been postulated to result from impaired executive functioning and excessive habit formation at the expense of goal-directed control and have been objectively demonstrated using neuropsychological tests in such patients. This study...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry Cogn Neurosci Neuroimaging
Main Authors: Vaghi, Matilde M., Hampshire, Adam, Fineberg, Naomi A., Kaser, Muzaffer, Brühl, Annette B., Sahakian, Barbara J., Chamberlain, Samuel R., Robbins, Trevor W.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier, Inc 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684958/
https://ncbi.nlm.nih.gov/pubmed/29167834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpsc.2017.05.005
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