Chimeric Antigen Receptor-Modified T Cells Redirected to EphA2 for the Immunotherapy of Non-Small Cell Lung Cancer

Erythropoietin-producing hepatocellular carcinoma A2 (EphA2) is overexpressed in more than 90% of non-small cell lung cancer (NSCLC) but not significantly in normal lung tissue. It is therefore an important tumor antigen target for chimeric antigen receptors (CAR)-T-based therapy in NSCLC. Here, we...

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Vydáno v:Transl Oncol
Hlavní autoři: Li, Ning, Liu, Shaohui, Sun, Mingjiao, Chen, Wei, Xu, Xiaogang, Zeng, Zhu, Tang, Yemin, Dong, Yongquan, Chang, Alex H., Zhao, Qiong
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2017
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Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5684428/
https://ncbi.nlm.nih.gov/pubmed/29132013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2017.10.009
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